What is Glaucoma?

What is Glaucoma?

Glaucoma is a group of eye diseases with the common outcome of damage to the optic nerve and retinal ganglion cells. The optic nerve is the cable which carries the information gathered by our eyes back to our brain to be processed. Glaucomatous damage to this cable thus can result in permanent peripheral or central visual field loss. It remains a public health concern as it is the second leading cause of blindness worldwide after cataracts and is known as the “silent thief of vision” because it typically is asymptomatic and may not produce symptoms of pain as the damage goes on.
We have strong evidence through landmark clinical trials (Abbreviations: OHTS, EMGT, AGIS, CNTGS) that raised intraocular pressure is a major risk factor for development and progression of this disease. Most normal people will have an intraocular pressure between 10 and 21 mmHg but we know that what is a normal eye pressure for one person may not be a normal eye pressure for another person. For example, a patient may experience glaucomatous nerve damage in a pressure range that is “normal” or less than 21 mmHg. On the other hand, a person may have a higher than normal pressure over a long period of time and not experience any nerve damage. Simply put, each individual is unique and has a different susceptibility to intraocular pressure for when they may experience damage to their optic nerve. It is even possible for patients with a very low intraocular pressure to continue to experience glaucomatous nerve damage though this is less common.
A common misconception is that blood pressure is the same as intraocular pressure. These two are different measurements and are not to be confused with one another. Nonetheless, your optometrist or ophthalmologist may ask you about your blood pressure as we continue to learn more about the effect of blood pressure and blood pressure medications on the susceptibility for the optic nerve to sustain damage.

What causes high eye pressure? (intraocular pressure, IOP)
There are numerous mechanisms by which your eye pressure could be elevated and your doctor will work with you to identify the possible etiology. You can imagine the eye as being like a sink which has a faucet and a drain. The faucet is where the fluid is produced which in your eye is called the ciliary body. The drainage system of your eye is a complex system of “tubes” that begins with a circumferential band of tissue known as the trabecular meshwork and eventually drains to your bodies normal blood circulation. A mismatch between the function of the faucet and the drain can sometimes produce high eye pressure analogous to a sink that is overflowing due to either a clogged drain or a faucet working overtime. Treatments are directed and either turning down the faucet or helping improve flow through the drain. In some cases, a new drain must be placed in the eye. More on this can be found in the Treatment section.

Many patients with glaucoma will have an eye pressure their optic nerve does not tolerate without any grossly obvious anatomical cause for having a pressure problem. You may see the words “primary” open angle glaucoma or “normal” tension glaucoma if this is the case.

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